Red Yeast Rice

Common name

N/A

ID

HD0053

Scientific name of the plant

Monascus purpureus

Anatomical part for use

N/A

Human use

Circulatory disorders

Summary

Monascus purpureus (syn. M. albidus, M. anka, M. araneosus, M. major, M. rubiginosus, and M. vini; simplified Chinese: 红曲霉; traditional Chinese: 紅麴黴; pinyin: hóng qū méi, lit. "red yeast") is a species of mold that is purplish-red in color. It is also known by the names ang-khak rice mold, corn silage mold, maize silage mold, and rice kernel discoloration. (Source: Wiki)

Evidence Level

Level 4 (Individual reports repeated observed over 5 years among different countries)

Hepatotoxicity reports in literature

  • Symptomatic hepatitis associated with the use of herbal red yeast rice : (Source)
  • Acute hepatitis caused by a natural lipid-lowering product: when "alternative" medicine is no "alternative" at all : (Source)
  • Adverse reactions to dietary supplements containing red yeast rice: assessment of cases from the Italian surveillance system : (Source)

Hepatotoxicity Description

In prospective controlled trials, red yeast rice extract formulations have not been associated with serum enzyme elevations or clinically apparent liver injury. However, there have been isolated case reports of liver injury in patients on red yeast rice extracts. A proportion of patients with liver injury attributed to red yeast rice extract were reported to have similar episodes of serum enzyme elevations during conventional lovastatin therapy. (Source: LiverTox)

Relevant Public Information

Wiki
NIH MedlinePlus
NIH LiverTox
Nature Medicines